Jurgen Melzer defeated John Isner 6-7 6-3 7-6 in the Memphis round of 32 on hard. The result followed the form book — Jurgen Melzer came in defending last year's round of 16. Jurgen Melzer extended the head-to-head to 3–2.
| Date | Tournament | Round | Surface | Winner | Score |
|---|---|---|---|---|---|
| 2015-03-12 | Indian Wells Masters | R64 | hard | John Isner | 6-3 6-4 |
| 2014-05-11 | Rome Masters | R64 | clay | Jurgen Melzer | 7-6(7) 6-3 |
| 2012-08-19 | Winston-Salem | R16 | hard | John Isner | 6-4 6-3 |
| 2012-02-20 | Memphis | QF | hard | Jurgen Melzer | 6-3 7-6(6) |
Each player's serve crossed against the other's return, converted to expected hold of serve. Recent completed matches, ATP, WTA & Challenger. About
Averages over each player's completed matches in the selected window (200 vs 200). ATP, WTA & Challenger.