Andreas Seppi defeated Martin Klizan 7-6 6-2 in the Sydney round of 16 on hard. The result followed the form book — Andreas Seppi came in leading the head-to-head 3–2. Andreas Seppi extended the head-to-head to 4–2.
| Date | Tournament | Round | Surface | Winner | Score |
|---|---|---|---|---|---|
| 2018-10-15 | Moscow | R32 | hard | Andreas Seppi | 6-1 7-6(6) |
| 2018-02-12 | Rotterdam | Q2 | hard | Martin Klizan | 6-3 7-6(2) |
| 2016-02-01 | Sofia | QF | hard | Martin Klizan | 6-4 6-3 |
| 2015-07-27 | Hamburg | R32 | clay | Andreas Seppi | 6-2 6-4 |
| 2012-10-29 | Paris Masters | R64 | hard | Andreas Seppi | 6-2 2-6 7-6(5) |
Averages from each player's recent completed matches (20 vs 20). ATP, WTA & Challenger.