Jo-Wilfried Tsonga defeated John Isner 6-7 3-6 7-6 6-2 19-17 in the Wimbledon round of 32 on grass. The upset overturned the form book — John Isner came in leading the head-to-head 3–1, defending last year's round of 32. Jo-Wilfried Tsonga narrowed the head-to-head to 3–2.
| Date | Tournament | Round | Surface | Winner | Score |
|---|---|---|---|---|---|
| 2012-08-19 | Winston-Salem | SF | hard | John Isner | 6-4 3-6 7-6(3) |
| 2012-04-06 | Davis Cup WG QF: FRA vs USA | RR | clay | John Isner | 6-3 7-6(4) 5-7 6-3 |
| 2011-11-07 | Paris Masters | SF | hard | Jo-Wilfried Tsonga | 3-6 7-6(1) 7-6(3) |
| 2009-08-02 | Washington | R32 | hard | John Isner | 4-6 7-6(2) 7-6(4) |
Each player's serve crossed against the other's return, converted to expected hold of serve. Recent completed matches, ATP, WTA & Challenger. About
Averages over each player's completed matches in the selected window (200 vs 200). ATP, WTA & Challenger.