Tomas Berdych defeated John Isner 6-4 6-4 6-4 in the Roland Garros round of 16 on clay. The result followed the form book — Tomas Berdych came in leading the head-to-head 6–2, defending last year's round of 128. Tomas Berdych extended the head-to-head to 7–2.
| Date | Tournament | Round | Surface | Winner | Score |
|---|---|---|---|---|---|
| 2015-05-03 | Madrid Masters | QF | clay | Tomas Berdych | 3-6 7-6(7) 7-6(1) |
| 2014-09-29 | Beijing | QF | hard | Tomas Berdych | 6-1 6-4 |
| 2014-03-19 | Miami Masters | R16 | hard | Tomas Berdych | 6-3 7-5 |
| 2013-09-30 | Beijing | QF | hard | Tomas Berdych | 7-5 6-2 |
| 2012-08-19 | Winston-Salem | F | hard | John Isner | 3-6 6-4 7-6(9) |
| 2010-05-24 | Roland Garros | R32 | clay | Tomas Berdych | 6-2 6-2 6-1 |
| 2010-05-16 | Dusseldorf | RR | clay | Tomas Berdych | 1-6 6-1 7-6(4) |
| 2009-08-02 | Washington | QF | hard | John Isner | 6-3 6-7(10) 6-2 |
Each player's serve crossed against the other's return, converted to expected hold of serve. Recent completed matches, ATP, WTA & Challenger. About
Averages over each player's completed matches in the selected window (200 vs 200). ATP, WTA & Challenger.
Performance in the biggest moments — break points, deciding sets and tiebreaks (0–100, higher is better). About