John Isner defeated Matthew Ebden 6-4 7-5 in the Indian Wells Masters round of 16 on hard. The result followed the form book — John Isner came in leading the head-to-head 4–1, defending last year's round of 32. John Isner extended the head-to-head to 5–1.
| Date | Tournament | Round | Surface | Winner | Score |
|---|---|---|---|---|---|
| 2019-07-15 | Newport | QF | grass | John Isner | 4-6 6-3 6-4 |
| 2018-07-23 | Atlanta | SF | hard | John Isner | 6-4 6-7(6) 6-1 |
| 2018-01-15 | Australian Open | R128 | hard | Matthew Ebden | 6-4 3-6 6-3 6-3 |
| 2017-07-17 | Newport | F | grass | John Isner | 6-3 7-6(4) |
| 2015-06-29 | Wimbledon | R64 | grass | John Isner | 6-2 7-6(8) 6-4 |
Each player's serve crossed against the other's return, converted to expected hold of serve. Recent completed matches, ATP, WTA & Challenger. About
Averages over each player's completed matches in the selected window (200 vs 200). ATP, WTA & Challenger.