Jurgen Melzer defeated Andreas Seppi 6-2 6-3 in the Zagreb round of 16 on hard. Jurgen Melzer extended the head-to-head to 4–3.
| Date | Tournament | Round | Surface | Winner | Score |
|---|---|---|---|---|---|
| 2011-02-14 | Marseille | R16 | hard | Jurgen Melzer | 7-5 6-3 |
| 2010-07-26 | Umag | QF | clay | Andreas Seppi | 6-1 6-4 |
| 2010-07-19 | Hamburg | SF | clay | Jurgen Melzer | 6-4 6-2 |
| 2010-02-08 | Rotterdam | R16 | hard | Jurgen Melzer | 6-2 6-2 |
| 2009-04-12 | Monte Carlo Masters | R64 | clay | Andreas Seppi | 6-2 6-0 |
| 2007-09-10 | Bucharest | R32 | clay | Andreas Seppi | 4-6 7-5 6-4 |
Each player's serve crossed against the other's return, converted to expected hold of serve. Recent completed matches, ATP, WTA & Challenger. About
Averages over each player's completed matches in the selected window (200 vs 200). ATP, WTA & Challenger.