Gilles Simon defeated Jurgen Melzer 6-7 6-3 7-5 in the Cincinnati Masters round of 64 on hard. The result followed the form book — Gilles Simon came in leading the head-to-head 3–2, defending last year's round of 64. Gilles Simon extended the head-to-head to 4–2.
| Date | Tournament | Round | Surface | Winner | Score |
|---|---|---|---|---|---|
| 2012-10-07 | Shanghai Masters | R64 | hard | Gilles Simon | 6-4 6-2 |
| 2012-03-21 | Miami Masters | R32 | hard | Gilles Simon | 7-6(5) 6-4 |
| 2011-03-04 | Davis Cup WG R1: AUT vs FRA | RR | clay | Jurgen Melzer | 7-6(7) 3-6 1-6 6-4 6-0 |
| 2009-09-28 | Bangkok | SF | hard | Gilles Simon | 6-4 7-6(3) |
| 2006-09-11 | Bucharest | R16 | clay | Jurgen Melzer | 3-6 6-3 6-4 |
Averages from each player's recent completed matches (20 vs 20). ATP, WTA & Challenger.