Daniela Hantuchova defeated Venus Williams 6-2 5-7 6-2 in the Eastbourne quarter-final on grass. The upset overturned the form book — Venus Williams came in leading the head-to-head 10–0. Daniela Hantuchova claimed a first win over Venus Williams in 11 meetings, narrowing the head-to-head to 10–1.
| Date | Tournament | Round | Surface | Winner | Score |
|---|---|---|---|---|---|
| 2010-03-22 | Miami | R16 | hard | Venus Williams | 1-6 7-5 6-4 |
| 2007-07-30 | San Diego | R16 | hard | Venus Williams | 6-0 6-3 |
| 2005-08-29 | US Open | R32 | hard | Venus Williams | 6-3 6-3 |
| 2005-06-20 | Wimbledon | R32 | grass | Venus Williams | 7-5 6-3 |
| 2004-03-24 | Miami | R32 | hard | Venus Williams | 7-6(0) 6-2 |
| 2003-02-10 | Antwerp | SF | hard | Venus Williams | 6-1 6-4 |
| 2003-01-13 | Australian Open | QF | hard | Venus Williams | 6-4 6-3 |
| 2002-08-19 | New Haven | SF | hard | Venus Williams | 6-3 6-3 |
| 2002-01-14 | Australian Open | R32 | hard | Venus Williams | 3-6 6-0 6-4 |
| 2001-06-25 | Wimbledon | R64 | grass | Venus Williams | 6-3 6-2 |
Each player's serve crossed against the other's return, converted to expected hold of serve. Recent completed matches, ATP, WTA & Challenger. About
Averages over each player's completed matches in the selected window (200 vs 199). ATP, WTA & Challenger.
Performance in the biggest moments — break points, deciding sets and tiebreaks (0–100, higher is better). About