Patty Schnyder defeated Serena Williams 2-6 6-4 7-5 in the Charleston quarter-final on clay. The upset overturned the form book — Serena Williams came in leading the head-to-head 8–3. Patty Schnyder narrowed the head-to-head to 8–4.
| Date | Tournament | Round | Surface | Winner | Score |
|---|---|---|---|---|---|
| 2009-05-04 | Rome | R32 | clay | Patty Schnyder | 6-2 2-6 6-1 |
| 2008-07-14 | Stanford | QF | hard | Serena Williams | 6-3 6-1 |
| 2008-03-03 | Bangalore | F | hard | Serena Williams | 7-5 6-3 |
| 2007-10-15 | Zurich | R32 | hard | Patty Schnyder | 6-0 3-0 RET |
| 2007-05-14 | Rome | QF | clay | Patty Schnyder | 6-3 2-6 7-6(5) |
| 2004-08-30 | US Open | R16 | hard | Serena Williams | 6-4 6-2 |
| 2000-08-14 | Montreal | R32 | hard | Serena Williams | 6-1 6-2 |
| 2000-02-14 | Hanover | QF | carpet | Serena Williams | 6-1 6-4 |
| 2000-02-07 | Paris | R16 | carpet | Serena Williams | 6-2 6-2 |
| 1999-08-09 | Manhattan Beach | R16 | hard | Serena Williams | 6-3 6-1 |
| 1998-03-19 | Key Biscayne | R16 | hard | Serena Williams | 6-0 4-6 6-3 |
Each player's serve crossed against the other's return, converted to expected hold of serve. Recent completed matches, ATP, WTA & Challenger. About
Averages over each player's completed matches in the selected window (200 vs 199). ATP, WTA & Challenger.
Performance in the biggest moments — break points, deciding sets and tiebreaks (0–100, higher is better). About