Anastasia Nefedova defeated Anastasia Zolotareva 3-6 7-5 6-1 in the W15 Cairo 18 quarter-final on clay. The upset overturned the form book — Anastasia Zolotareva came in leading the head-to-head 2–0. Anastasia Nefedova claimed a first win over Anastasia Zolotareva in three meetings, narrowing the head-to-head to 2–1.
| Date | Tournament | Round | Surface | Winner | Score |
|---|---|---|---|---|---|
| 2021-12-12 | W15 Cairo 19 | F | clay | Anastasia Zolotareva | 6-4 6-2 |
| 2021-09-05 | W15 Cairo 12 | F | clay | Anastasia Zolotareva | 6-4 6-4 |
Averages over each player's completed matches in the selected window. ATP, WTA & Challenger.