

Marcos Giron advanced when Yoshihito Nishioka retired 6-7 6-4 0-0 in the Madrid Masters qualifying round 2. Marcos Giron narrowed the head-to-head to 3–2.
| Date | Tournament | Round | Surface | Winner | Score |
|---|---|---|---|---|---|
| 2024-06-24 | Eastbourne | R16 | grass | Yoshihito Nishioka | 6-7(8) 6-4 6-2 |
| 2023-10-16 | Tokyo | R32 | hard | Marcos Giron | 7-6(14) 4-6 6-1 |
| 2019-08-26 | US Open | R128 | hard | Yoshihito Nishioka | 3-6 6-4 6-4 6-4 |
| 2015-02-16 | Delray Beach | Q2 | hard | Yoshihito Nishioka | 4-6 6-3 6-2 |
Averages from each player's recent completed matches (20 vs 19). ATP, WTA & Challenger.