John Isner defeated Leonardo Mayer 6-7 7-6 6-3 in the Houston round of 16 on clay. The result followed the form book — John Isner came in leading the head-to-head 2–0, defending last year's semi-final. John Isner extended the head-to-head to 3–0.
| Date | Tournament | Round | Surface | Winner | Score |
|---|---|---|---|---|---|
| 2017-10-02 | Beijing | R16 | hard | John Isner | 6-0 6-3 |
| 2015-05-10 | Rome Masters | R32 | clay | John Isner | 7-6(6) 6-4 |
Each player's serve crossed against the other's return, converted to expected hold of serve. Recent completed matches, ATP, WTA & Challenger. About
Averages over each player's completed matches in the selected window (200 vs 174). ATP, WTA & Challenger.