John Isner defeated Thomaz Bellucci 7-6 6-7 6-1 in the Madrid Masters round of 32 on clay. The upset overturned the form book — Thomaz Bellucci came in leading the head-to-head 2–1. John Isner narrowed the head-to-head to 2–2.
| Date | Tournament | Round | Surface | Winner | Score |
|---|---|---|---|---|---|
| 2017-03-20 | Miami Masters | R64 | hard | John Isner | 7-5 7-6(5) |
| 2013-02-01 | Davis Cup WG R1: USA vs BRA | RR | hard | Thomaz Bellucci | 2-6 6-4 6-7(7) 6-4 6-3 |
| 2010-04-25 | Rome Masters | R32 | clay | Thomaz Bellucci | 7-6(7) 7-5 |
Averages from each player's recent completed matches (20 vs 20). ATP, WTA & Challenger.