Andreas Seppi defeated Lleyton Hewitt 7-6 6-3 5-7 5-7 7-5 in the Australian Open round of 128 on hard. Andreas Seppi extended the head-to-head to 4–3.
| Date | Tournament | Round | Surface | Winner | Score |
|---|---|---|---|---|---|
| 2013-10-07 | Shanghai Masters | R64 | hard | Andreas Seppi | 6-4 6-2 |
| 2011-06-06 | Halle | R16 | grass | Lleyton Hewitt | 6-4 6-4 |
| 2010-01-11 | Sydney | R16 | hard | Lleyton Hewitt | 6-0 6-2 |
| 2008-02-18 | Rotterdam | R32 | hard | Andreas Seppi | 3-6 7-6(4) 7-6(4) |
| 2006-01-09 | Sydney | QF | hard | Andreas Seppi | 4-6 7-5 7-5 |
| 2004-05-03 | Rome Masters | R64 | clay | Lleyton Hewitt | 5-7 7-5 6-3 |
Each player's serve crossed against the other's return, converted to expected hold of serve. Recent completed matches, ATP, WTA & Challenger. About
Averages over each player's completed matches in the selected window (200 vs 42). ATP, WTA & Challenger.