Serena Williams defeated Victoria Azarenka 7-5 6-7 6-1 in the US Open final on hard. The result followed the form book — Serena Williams came in leading the head-to-head 15–5, defending the title. Serena Williams extended the head-to-head to 16–5.
| Date | Tournament | Round | Surface | Winner | Score |
|---|---|---|---|---|---|
| 2020-08-31 | US Open | SF | hard | Victoria Azarenka | 1-6 6-3 6-3 |
| 2019-03-04 | Indian Wells | R64 | hard | Serena Williams | 7-5 6-3 |
| 2016-03-07 | Indian Wells | F | hard | Victoria Azarenka | 6-4 6-4 |
| 2015-06-29 | Wimbledon | QF | grass | Serena Williams | 3-6 6-2 6-3 |
| 2015-05-25 | Roland Garros | R32 | clay | Serena Williams | 3-6 6-4 6-2 |
| 2015-05-04 | Madrid | R16 | clay | Serena Williams | 7-6(5) 3-6 7-6(1) |
| 2013-12-30 | Brisbane | F | hard | Serena Williams | 6-4 7-5 |
| 2013-08-12 | Cincinnati | F | hard | Victoria Azarenka | 2-6 6-2 7-6(6) |
| 2013-05-13 | Rome | F | clay | Serena Williams | 6-1 6-3 |
| 2013-02-11 | Doha | F | hard | Victoria Azarenka | 7-6(6) 2-6 6-3 |
| 2012-10-22 | WTA Championships | RR | hard | Serena Williams | 6-4 6-4 |
| 2012-08-27 | US Open | F | hard | Serena Williams | 6-2 2-6 7-5 |
| 2012-07-30 | Olympics | SF | hard | Serena Williams | 6-1 6-2 |
| 2012-06-25 | Wimbledon | SF | grass | Serena Williams | 6-3 7-6(6) |
| 2012-05-07 | Madrid | F | clay | Serena Williams | 6-1 6-3 |
| 2011-08-29 | US Open | R32 | hard | Serena Williams | 6-1 7-6(5) |
| 2011-08-08 | Toronto | SF | hard | Serena Williams | 6-3 6-3 |
| 2010-01-18 | Australian Open | QF | hard | Serena Williams | 4-6 7-6(4) 6-2 |
| 2009-06-22 | Wimbledon | QF | grass | Serena Williams | 6-2 6-3 |
| 2009-03-23 | Miami | F | hard | Victoria Azarenka | 6-3 6-1 |
Each player's serve crossed against the other's return, converted to expected hold of serve. Recent completed matches, ATP, WTA & Challenger. About
Averages over each player's completed matches in the selected window (199 vs 195). ATP, WTA & Challenger.
Performance in the biggest moments — break points, deciding sets and tiebreaks (0–100, higher is better). About