Stan Wawrinka defeated Denis Istomin 6-3 7-5 in the Monte Carlo Masters round of 64 on clay. The result followed the form book — Stan Wawrinka came in leading the head-to-head 2–1, defending last year's quarter-final. Stan Wawrinka extended the head-to-head to 3–1.
| Date | Tournament | Round | Surface | Winner | Score |
|---|---|---|---|---|---|
| 2014-06-23 | Wimbledon | R32 | grass | Stan Wawrinka | 6-3 6-3 6-4 |
| 2012-10-07 | Shanghai Masters | R32 | hard | Stan Wawrinka | 6-4 4-6 6-4 |
| 2010-06-21 | Wimbledon | R128 | grass | Denis Istomin | 6-7(5) 6-1 2-6 7-6(4) 6-3 |
Averages from each player's recent completed matches (19 vs 20). ATP, WTA & Challenger.