Fabio Fognini defeated Tomas Berdych 6-4 6-2 in the Monte Carlo Masters round of 16 on clay. The upset overturned the form book — Tomas Berdych came in leading the head-to-head 3–1, defending last year's semi-final. Fabio Fognini narrowed the head-to-head to 3–2.
| Date | Tournament | Round | Surface | Winner | Score |
|---|---|---|---|---|---|
| 2018-01-15 | Australian Open | R16 | hard | Tomas Berdych | 6-1 6-4 6-4 |
| 2015-05-10 | Rome Masters | R16 | clay | Tomas Berdych | 6-3 3-6 7-6(2) |
| 2011-08-29 | US Open | R64 | hard | Tomas Berdych | 7-5 6-0 6-0 |
| 2009-04-12 | Monte Carlo Masters | R64 | clay | Fabio Fognini | 1-6 6-3 6-3 |
Averages from each player's recent completed matches (20 vs 20). ATP, WTA & Challenger.