Michael Llodra defeated John Isner 6-4 7-6 in the Paris Masters round of 32 on hard. Michael Llodra extended the head-to-head to 2–1.
| Date | Tournament | Round | Surface | Winner | Score |
|---|---|---|---|---|---|
| 2010-11-07 | Paris Masters | R32 | hard | Michael Llodra | 6-3 6-4 |
| 2010-11-01 | Basel | R32 | hard | John Isner | 4-6 7-5 6-3 |
Averages from each player's recent completed matches (20 vs 20). ATP, WTA & Challenger.