Serena Williams defeated Maria Jose Martinez Sanchez 6-2 6-4 in the US Open round of 64 on hard. The result followed the form book — Serena Williams came in leading the head-to-head 3–0, defending last year's final. Serena Williams extended the head-to-head to 4–0.
| Date | Tournament | Round | Surface | Winner | Score |
|---|---|---|---|---|---|
| 2010-01-11 | Sydney | R16 | hard | Serena Williams | 6-1 6-2 |
| 2009-08-31 | US Open | R32 | hard | Serena Williams | 6-3 7-5 |
| 2009-05-25 | Roland Garros | R32 | clay | Serena Williams | 4-6 6-3 6-4 |
Each player's serve crossed against the other's return, converted to expected hold of serve. Recent completed matches, ATP, WTA & Challenger. About
Averages over each player's completed matches in the selected window (199 vs 25). ATP, WTA & Challenger.
Performance in the biggest moments — break points, deciding sets and tiebreaks (0–100, higher is better). About