Ivo Karlovic defeated Florian Mayer 6-1 6-3 in the Cincinnati Masters round of 64 on hard. The upset overturned the form book — Florian Mayer came in leading the head-to-head 1–0, defending last year's round of 64. Ivo Karlovic claimed a first win over Florian Mayer in two meetings, narrowing the head-to-head to 1–1.
| Date | Tournament | Round | Surface | Winner | Score |
|---|---|---|---|---|---|
| 2011-03-23 | Miami Masters | R128 | hard | Florian Mayer | 6-4 7-6(6) |
Averages from each player's recent completed matches (20 vs 20). ATP, WTA & Challenger.