Vera Zvonareva defeated Serena Williams 3-6 7-6 7-5 in the Eastbourne round of 16 on grass. The upset overturned the form book — Serena Williams came in leading the head-to-head 8–1. Vera Zvonareva narrowed the head-to-head to 8–2.
| Date | Tournament | Round | Surface | Winner | Score |
|---|---|---|---|---|---|
| 2015-01-19 | Australian Open | R64 | hard | Serena Williams | 7-5 6-0 |
| 2012-07-30 | Olympics | R16 | hard | Serena Williams | 6-1 6-0 |
| 2010-06-21 | Wimbledon | F | grass | Serena Williams | 6-3 6-2 |
| 2008-04-14 | Charleston | F | clay | Serena Williams | 6-4 3-6 6-3 |
| 2007-08-27 | US Open | R32 | hard | Serena Williams | 6-4 7-6(4) |
| 2006-07-17 | Cincinnati | SF | hard | Vera Zvonareva | 6-2 6-3 |
| 2004-09-20 | Beijing | SF | hard | Serena Williams | 6-2 6-3 |
| 2004-07-19 | Los Angeles | QF | hard | Serena Williams | 4-6 6-3 6-3 |
| 2002-05-27 | Roland Garros | R16 | clay | Serena Williams | 4-6 6-0 6-1 |
Each player's serve crossed against the other's return, converted to expected hold of serve. Recent completed matches, ATP, WTA & Challenger. About
Averages over each player's completed matches in the selected window (199 vs 199). ATP, WTA & Challenger.
Performance in the biggest moments — break points, deciding sets and tiebreaks (0–100, higher is better). About