Serena Williams defeated Meng Yuan 6-3 6-2 in the Australian Open round of 128 on hard. The result followed the form book — Serena Williams came in leading the head-to-head 1–0, defending last year's quarter-final. Serena Williams extended the head-to-head to 2–0.
| Date | Tournament | Round | Surface | Winner | Score |
|---|---|---|---|---|---|
| 2008-01-14 | Australian Open | R64 | hard | Serena Williams | 6-3 6-1 |
Averages over each player's completed matches in the selected window. ATP, WTA & Challenger.