Nicolas Mahut defeated John Isner 7-5 6-4 in the London round of 32 on carpet. The upset overturned the form book — John Isner came in leading the head-to-head 3–1. Nicolas Mahut narrowed the head-to-head to 3–2.
| Date | Tournament | Round | Surface | Winner | Score |
|---|---|---|---|---|---|
| 2012-07-09 | Newport | R16 | grass | John Isner | 6-2 7-6 |
| 2011-06-20 | Wimbledon | R128 | grass | John Isner | 7-6 6-2 7-6 |
| 2010-06-21 | Wimbledon | R128 | grass | John Isner | 6-4 3-6 6-7 7-6 70-68 |
| 2008-06-09 | Queen's Club | R32 | grass | Nicolas Mahut | 7-5 6-4 |
Averages over each player's completed matches in the selected window (200 vs 200). ATP, WTA & Challenger.
Each player's serve crossed against the other's return, converted to expected hold of serve. Recent completed matches, ATP, WTA & Challenger. About