Dinara Safina defeated Serena Williams 2-6 6-1 7-6 in the Berlin quarter-final on grass. The upset overturned the form book — Serena Williams came in leading the head-to-head 6–0. Dinara Safina claimed a first win over Serena Williams in seven meetings, narrowing the head-to-head to 6–1.
| Date | Tournament | Round | Surface | Winner | Score |
|---|---|---|---|---|---|
| 2009-01-19 | Australian Open | F | hard | Serena Williams | 6-0 6-3 |
| 2008-11-03 | WTA Tour Championships | RR | carpet | Serena Williams | 6-4 6-1 |
| 2008-08-25 | US Open | SF | hard | Serena Williams | 6-3 6-2 |
| 2007-05-28 | Roland Garros | R16 | clay | Serena Williams | 6-2 6-3 |
| 2004-09-20 | Beijing | R16 | hard | Serena Williams | 6-4 3-6 6-3 |
| 2002-08-26 | US Open | R64 | hard | Serena Williams | 6-0 6-1 |
Each player's serve crossed against the other's return, converted to expected hold of serve. Recent completed matches, ATP, WTA & Challenger. About
Averages over each player's completed matches in the selected window (174 vs 199). ATP, WTA & Challenger.
Performance in the biggest moments — break points, deciding sets and tiebreaks (0–100, higher is better). About