James Blake defeated Fabrice Santoro 6-4 3-6 6-2 4-6 6-4 in the US Open round of 64 on hard. The result followed the form book — James Blake came in leading the head-to-head 4–1, defending last year's quarter-final. James Blake extended the head-to-head to 5–1.
| Date | Tournament | Round | Surface | Winner | Score |
|---|---|---|---|---|---|
| 2009-11-08 | Paris Masters | R64 | hard | James Blake | 6-4 6-3 |
| 2008-03-27 | Miami Masters | R32 | hard | James Blake | 6-3 6-7(4) 6-4 |
| 2008-01-07 | Sydney | R32 | hard | Fabrice Santoro | 7-6(4) 6-2 |
| 2006-08-14 | Cincinnati Masters | R64 | hard | James Blake | 6-4 6-4 |
| 2002-03-18 | Miami Masters | R64 | hard | James Blake | 2-6 7-5 6-3 |
Each player's serve crossed against the other's return, converted to expected hold of serve. Recent completed matches, ATP, WTA & Challenger. About
Averages over each player's completed matches in the selected window (200 vs 113). ATP, WTA & Challenger.
Performance in the biggest moments — break points, deciding sets and tiebreaks (0–100, higher is better). About