Lorena Villalobos Cruz defeated Nina Pantic 3-6 7-6 6-0 in the Saltillo 25K round of 32 on hard. The upset overturned the form book — Nina Pantic came in leading the head-to-head 1–0, but Lorena Villalobos Cruz had been the form player, winning 3 of their last 8 on hard. Lorena Villalobos Cruz claimed a first win over Nina Pantic in two meetings, narrowing the head-to-head to 1–1.
| Date | Tournament | Round | Surface | Winner | Score |
|---|---|---|---|---|---|
| 2006-05-29 | Leon 10K | QF | hard | Nina Pantic | 6-7(0) 6-3 6-0 |