Marc Fornell Mestres defeated Jose Luis Muguruza 6-4 0-6 6-3 in the Spain 1 1 round of 16 on clay. The upset overturned the form book — Jose Luis Muguruza came in leading the head-to-head 1–0. Marc Fornell Mestres claimed a first win over Jose Luis Muguruza in two meetings, narrowing the head-to-head to 1–1.
| Date | Tournament | Round | Surface | Winner | Score |
|---|---|---|---|---|---|
| 2006-05-22 | Spain F16 | SF | clay | Jose Luis Muguruza | 2-6 7-5 6-3 |
Averages over each player's completed matches in the selected window. ATP, WTA & Challenger.