Agustina Lepore defeated Mariana Duque Marino 5-7 7-5 6-3 in the Santiago 10K round of 16 on clay. The upset overturned the form book — Mariana Duque Marino came in leading the head-to-head 3–1. Agustina Lepore narrowed the head-to-head to 3–2.
| Date | Tournament | Round | Surface | Winner | Score |
|---|---|---|---|---|---|
| 2007-10-15 | San Luis Potosi 25K | R16 | hard | Mariana Duque Marino | 7-6(10) 6-1 |
| 2006-05-29 | Leon 10K | SF | hard | Agustina Lepore | 6-4 6-4 |
| 2006-05-08 | Los Mochis 10K | F | clay | Mariana Duque Marino | 6-2 6-1 |
| 2005-08-22 | Bogota 10K | R16 | clay | Mariana Duque Marino | 6-7(5) 6-4 6-4 |
Averages over each player's completed matches in the selected window. ATP, WTA & Challenger.