Francesca Schiavone defeated Serena Williams 7-6 6-1 in the Rome round of 32 on clay. The upset overturned the form book — Serena Williams came in leading the head-to-head 7–1, defending last year's semi-final. Francesca Schiavone narrowed the head-to-head to 7–2.
| Date | Tournament | Round | Surface | Winner | Score |
|---|---|---|---|---|---|
| 2013-09-30 | Beijing | R32 | hard | Serena Williams | 6-4 7-5 |
| 2013-08-26 | US Open | R128 | hard | Serena Williams | 6-0 6-1 |
| 2013-08-05 | Toronto | R32 | hard | Serena Williams | 6-3 6-2 |
| 2009-05-11 | Madrid | R64 | clay | Francesca Schiavone | 6-4 0-0 RET |
| 2008-05-05 | Berlin | R32 | grass | Serena Williams | 6-2 6-3 |
| 2005-08-29 | US Open | R32 | hard | Serena Williams | 6-3 6-4 |
| 2003-03-19 | Miami | R64 | hard | Serena Williams | 7-5 6-1 |
| 2002-06-24 | Wimbledon | R64 | grass | Serena Williams | 6-3 6-3 |
Each player's serve crossed against the other's return, converted to expected hold of serve. Recent completed matches, ATP, WTA & Challenger. About
Averages over each player's completed matches in the selected window (200 vs 199). ATP, WTA & Challenger.
Performance in the biggest moments — break points, deciding sets and tiebreaks (0–100, higher is better). About