Mario Ancic defeated Rafael Nadal 7-5 6-2 in the Milan round of 16 on carpet. The upset overturned the form book — Rafael Nadal came in leading the head-to-head 4–0. Mario Ancic claimed a first win over Rafael Nadal in five meetings, narrowing the head-to-head to 4–1.
| Date | Tournament | Round | Surface | Winner | Score |
|---|---|---|---|---|---|
| 2010-03-11 | Indian Wells Masters | R32 | hard | Rafael Nadal | 6-2 6-2 |
| 2008-04-20 | Monte Carlo Masters | R32 | clay | Rafael Nadal | 6-0 6-3 |
| 2004-01-12 | Auckland | R16 | hard | Rafael Nadal | 7-6(0) 7-6(6) |
| 2003-06-23 | Wimbledon | R128 | grass | Rafael Nadal | 6-3 6-4 4-6 6-4 |
Each player's serve crossed against the other's return, converted to expected hold of serve. Recent completed matches, ATP, WTA & Challenger. About
Averages over each player's completed matches in the selected window (200 vs 200). ATP, WTA & Challenger.