Mikhail Youzhny defeated Fabrice Santoro 6-0 7-6 in the Halle round of 32 on grass. The upset overturned the form book — Fabrice Santoro came in defending last year's final. Mikhail Youzhny extended the head-to-head to 4–3.
| Date | Tournament | Round | Surface | Winner | Score |
|---|---|---|---|---|---|
| 2008-03-03 | Dubai | R32 | hard | Fabrice Santoro | 6-3 6-4 |
| 2007-02-12 | Marseille | R16 | hard | Mikhail Youzhny | 6-7(4) 6-2 6-3 |
| 2006-06-12 | Halle | R32 | grass | Fabrice Santoro | 7-6(4) 6-2 |
| 2004-08-02 | Cincinnati Masters | R32 | hard | Fabrice Santoro | 7-5 6-3 |
| 2001-06-25 | Wimbledon | R32 | grass | Mikhail Youzhny | 7-5 6-0 2-0 RET |
| 2000-10-23 | Moscow | R32 | hard | Mikhail Youzhny | 6-4 6-2 |
Each player's serve crossed against the other's return, converted to expected hold of serve. Recent completed matches, ATP, WTA & Challenger. About
Averages over each player's completed matches in the selected window (200 vs 200). ATP, WTA & Challenger.
Performance in the biggest moments — break points, deciding sets and tiebreaks (0–100, higher is better). About