Paul Henri Mathieu defeated Fabrice Santoro 7-5 6-1 1-6 6-4 in the Roland Garros round of 64 on clay. The upset overturned the form book — Fabrice Santoro came in leading the head-to-head 4–1, defending last year's round of 16. Paul Henri Mathieu narrowed the head-to-head to 4–2.
| Date | Tournament | Round | Surface | Winner | Score |
|---|---|---|---|---|---|
| 2008-10-06 | Moscow | QF | hard | Fabrice Santoro | 6-3 2-0 RET |
| 2006-10-02 | Metz | R32 | hard | Paul Henri Mathieu | 6-4 5-7 6-4 |
| 2006-02-20 | Rotterdam | R32 | hard | Fabrice Santoro | 6-3 6-3 |
| 2005-10-24 | Lyon | R16 | clay | Fabrice Santoro | 6-1 6-4 |
| 2005-08-22 | New Haven | R32 | hard | Fabrice Santoro | 6-4 7-6(2) |
Each player's serve crossed against the other's return, converted to expected hold of serve. Recent completed matches, ATP, WTA & Challenger. About
Averages over each player's completed matches in the selected window (200 vs 200). ATP, WTA & Challenger.
Performance in the biggest moments — break points, deciding sets and tiebreaks (0–100, higher is better). About