Venus Williams defeated Irina Spirlea 6-3 6-2 in the Zurich round of 16 on hard. The result followed the form book — Venus Williams came in leading the head-to-head 2–1, defending last year's final. Venus Williams extended the head-to-head to 3–1.
| Date | Tournament | Round | Surface | Winner | Score |
|---|---|---|---|---|---|
| 2000-04-30 | Hamburg | R16 | clay | Venus Williams | 6-7(4) 6-2 6-2 |
| 1997-11-10 | Philadelphia | R32 | carpet | Irina Spirlea | 6-3 6-2 |
| 1997-08-25 | US Open | SF | hard | Venus Williams | 7-6 4-6 7-6 |
Averages over each player's completed matches in the selected window. ATP, WTA & Challenger.